Route 21

MO-CC - Iron County

Taum Sauk Mountain State Park Jct

2 signs

MO-21 South/MO-72 West at MO-E

Arcadia

3 signs

MO-21 South at MO-N

Pilot Knob

1 sign

MO-21 South/MO-32 West Split

South of Caledonia

1 sign

MO-21 South at MO-32 East - Caledonia

Caledonia

2 signs

MO-21 South at MO-M

Between Caledonia and Potosi

2 signs

MO-21 South at MO-8

Potosi

3 signs

MO-21/MO-47 South at MO-21/MO-47 Split

Old Mines

2 signs

MO-21 South at MO-47 Junction

Rabbitville

2 signs

MO-21 South Approaching MO-H and MO-N

De Soto

5 signs

MO-21 South/MO-B East at MO-21 North

Hillsboro

3 signs

MO-21 South - MO-M/MO-MM Interchange

Otto

1 sign

MO-21 South at MO-141 Interchange

Paulina Hills

3 signs

I-270 West - Exit 2

Exit 2

1 sign