East St. Louis, Illinois

I-255 south at Exit 17B - IL-15 West/Missouri Ave./Saint Louis. Approaching Exit 17A - IL-15 East/Belleville.

I-255 South approaching Exits 17A-B - IL-15/East Saint Louis/Belleville.

I-255 south at Exit 20. Use Exit 20 for I-64/US-50 East/Louisville (KY) and I-64 West/Saint Louis (MO). Continue on I-255 South/US-50 West to Memphis (TN) and Tulsa (OK). US-50 west joins I-255 southbound to Saint Louis, Missouri.