I-26 west at Exit 31A - I-40 East/Hickory/Biltmore Estate. Approaching Exit 31B - I-40 West/US-74 West/Knoxville (TN)/Canton. Continue straight for I-26 West/I-240 East/Asheville Downtown/Johnson City (TN). US-74 leaves I-26 westbound and joins I-40 westbound.