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I-255 South - Exit 20
I-255 South - Exit 20

I-255 south at Exit 20. Use Exit 20 for I-64/US-50 East/Louisville (KY) and I-64 West/Saint Louis (MO). Continue on I-255 South/US-50 West to Memphis (TN) and Tulsa (OK). US-50 west joins I-255 southbound to Saint Louis, Missouri.

Taken 03-27-2026

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Nearby Signs
Shield Inside Sign Big Green Sign Freeway Junction Interchange Overhead
I-64 I-255 (Saint Louis) US-50 East St. Louis St. Clair County Illinois United States
I-255 (Saint Louis) US-50 Exit 17
I-64/I-255 Interchange
Current Location
I-255 (Saint Louis) I-55/I-70/I-255 Interchange
US-50 Exit 176
I-64 Exit 58A