Signs From Illinois

I-255 South at Exit 9 - Dupo

I-255 south at Exit 10 - IL-3 North/Great River Road/Cahokia Heights/East Saint Louis. IL-3 South joins I-255 South/US-50 West to Columbia.

I-255 south at Exit 13 - IL-157/Cahokia Heights. Approaching Exit 10 - IL-3 North/Great River Road/East Saint Louis.

I-255 south at Exit 17B - IL-15 West/Missouri Ave./Saint Louis. Approaching Exit 17A - IL-15 East/Belleville.

I-255 South approaching Exits 17A-B - IL-15/East Saint Louis/Belleville.

I-255 south at Exit 20. Use Exit 20 for I-64/US-50 East/Louisville (KY) and I-64 West/Saint Louis (MO). Continue on I-255 South/US-50 West to Memphis (TN) and Tulsa (OK). US-50 west joins I-255 southbound to Saint Louis, Missouri.

I-255 south approaching Exit 20 - I-64/US-50/Saint Louis (MO)/Louisville (KY).

I-255 south approaching Exit 25A - I-55 North/I-70 East/Chicago/Indianapolis (IN).

I-255 south approaching Exit 25B - I-70 West/I-55 South/Saint Louis. Continue south on I-255 for Memphis (TN).

I-255 South at Exit 26 - Horseshoe Lake Road. Approaching Exit 25A-B - I-70/I-55/St. Louis (MO)/Indianapolis (IN).