Signs From Missouri

End MO-CC at MO-21/MO-72 in Iron County. MO-21 is designated as the Ozark Run Scenic Byway.

MO-CC in Iron County. MO-CC connects MO-21/MO-72 with Taum Sauk Mountain State Park. Taum Sauk Mountain is the highest point in Missouri.

MO-21 South/MO-72 West at MO-E in Iron County.

MO-21 South at MO-72 in Arcadia. MO-72 West joins MO-21 southbound.

MO-21 South approaching MO-72 East in Arcadia.

MO-21 South at MO-N in Iron County. Turn right to continue south on MO-21.

MO-21 South/MO-32 West split in Iron County.

MO-21 South/MO-32 West in Caledonia. MO-21 is designated as the Ozark Run Scenic Byway

MO-21 South at MO-32 East in Caledonia. MO-32 West joins MO-21 southbound. MO-21 is designated the Ozark Run Scenic Byway.

MO-21 South at MO-C in Washington County. Use MO-C West to Belgrade. Continue south on MO-21 for Caledonia.