Signs From Missouri

MO-21 South at MO-N in Iron County. Turn right to continue south on MO-21.

MO-21 South/MO-32 West split in Iron County.

MO-21 South/MO-32 West in Caledonia. MO-21 is designated as the Ozark Run Scenic Byway

MO-21 South at MO-32 East in Caledonia. MO-32 West joins MO-21 southbound. MO-21 is designated the Ozark Run Scenic Byway.

MO-21 South at MO-C in Washington County. Use MO-C West to Belgrade. Continue south on MO-21 for Caledonia.

MO-21 South at MO-M. MO-21 is designated as the Ozark Run Scenic Byway.

MO-21 South at MO-8 junction in Potosi.

MO-21 South approaching MO-8 in Potosi. Use MO-8 East to Leadwood; MO-8 West to Potosi. Continue south on MO-21 to Caledonia.

Potosi City Limit on MO-21 South. Potosi is the County Seat of Washington County.

MO-21/MO-47 South at MO-21/MO-47 split in Old Mines. MO-21 is designated as the Ozark Run Scenic Byway