Signs From Missouri

MO-21 South at MO-H and MO-N in De Soto.

MO-21 South approaching MO-H and MO-N in De Soto.

MO-21 South at MO-Y in De Soto. Turn right for Richwoods; left for De Soto. Continue south on MO-21 for Potosi.

MO-21 South at MO-Y in De Soto.

MO-21 South at MO-110 in Jefferson County

MO-21 South/MO-B East at MO-21 North interchange to Saint Louis.

MO-21 South at MO-B. This is the southern end of the MO-21 freeway. Turn left to continue on MO-21 south.

MO-21 South approaching MO-B Interchange.

MO-21 South at MO-M/MO-MM/Barnhart/House Springs interchange.

MO-21 South at MO-141 to Arnold and Fenton interchange.