Signs Tagged With Intersection

MO-49 North at MO-21/MO-72 junction in Iron County. Turn left to continue north on MO-49.

MO-21/MO-72 South at MO-49 in Iron County. Turn right for MO-49 North and to continue on MO-21/MO-72 South. Continue straight on roadway for MO-49 South. The smokestacks in the background are the site of the Doe Run Company lead smelter.

MO-21/MO-72 South approaching MO-49 in Iron County. Use MO-49 south to Annapolis; MO-49 North/MO-21/MO-72 South to Lesterville and Centerville. The smokestacks in the background are part of the Doe Run Company lead smelter.

End MO-CC at MO-21/MO-72 in Iron County. MO-21 is designated as the Ozark Run Scenic Byway.

MO-21 South/MO-72 West at MO-E in Iron County.

MO-21 South at MO-72 in Arcadia. MO-72 West joins MO-21 southbound.

MO-21 South approaching MO-72 East in Arcadia.

MO-21 South at MO-N in Iron County. Turn right to continue south on MO-21.

MO-21 South/MO-32 West split in Iron County.

MO-21 South/MO-32 West in Caledonia. MO-21 is designated as the Ozark Run Scenic Byway

MO-21 South at MO-32 East in Caledonia. MO-32 West joins MO-21 southbound. MO-21 is designated the Ozark Run Scenic Byway.

MO-21 South at MO-C in Washington County. Use MO-C West to Belgrade. Continue south on MO-21 for Caledonia.

MO-21 South at MO-M. MO-21 is designated as the Ozark Run Scenic Byway.

MO-21 South at MO-8 junction in Potosi.

MO-21 South approaching MO-8 in Potosi. Use MO-8 East to Leadwood; MO-8 West to Potosi. Continue south on MO-21 to Caledonia.

MO-21/MO-47 South at MO-21/MO-47 split in Old Mines. MO-21 is designated as the Ozark Run Scenic Byway

MO-21/MO-47 South at MO-21/MO-47 split in Old Mines. MO-21 is designated the Ozark Run Scenic Byway

MO-21 South at MO-47 junction. MO-47 South joins MO-21 South to Old Mines. MO-21 is designated as the Ozark Run Scenic Byway.

MO-21 South approaching MO-47 North to Richwoods. MO-47 South joins MO-21 South towards Potosi.

MO-21 South at MO-H and MO-N in De Soto.

MO-21 South approaching MO-H and MO-N in De Soto.

MO-21 South at MO-Y in De Soto. Turn right for Richwoods; left for De Soto. Continue south on MO-21 for Potosi.

MO-21 South at MO-Y in De Soto.

MO-21 South at MO-110 in Jefferson County

US-20/US-26 east approaching OR-201.